On Saturday morning, a woman from London was arrested in Greater Manchester on suspicion of conspiracy to cause public nuisance, according to Merseyside Police.
They had anticipated protests, and about 30 animal rights protesters had already assembled outside the racecourse.
Prior to this, the police had issued a warning to deal firmly with any disruptions as animal rights activists had previously threatened to sabotage the race.
“Merseyside Police has been working with The Jockey Club and other partners to keep people safe during the Grand National Festival,” they said in a new statement.
“We are aware of some people planning to protest at the event. This has been factored into our plans. We respect the right to peaceful protest and expression of views, but criminal behaviour and disorder will not be tolerated and will be dealt with robustly.”
At 5:15 PM BST, 39 runners are expected to compete in the 175th edition of the renowned race.
Animal rights group Animal Rising, which focuses on climate and animal welfare, announced that approximately 300 activists would arrive at the venue on Saturday morning with the intention of obstructing the race by climbing over the fences and entering the track.
Aintree Racecourse warned their actions could “endanger the horses they purport to protect, as well as jockeys, officials and themselves”.