Lance Reddick, an actor famous for his appearances in the “John Wick” movies and the HBO show “The Wire,” has passed away at the age of 60.

According to his representatives, he died from natural causes early on Friday. Reddick had recently missed the New York City premiere of “John Wick: Chapter 4,” which stars Keanu Reeves.

“We are deeply saddened and heartbroken at the loss of our beloved friend and colleague Lance Reddick,” Reeves and director Chat Stahelski said in a joint statement to Deadline. “He was the consummate professional and a joy to work with. Our love and prayers are with his wife Stephanie, his children, family and friends. We dedicate the film to his loving memory. We will miss him dearly.”

Lionsgate, the studio making the franchise, also released a tribute.

“The world of Wick would not be what it is without Lance Reddick and the unparalleled depth he brought to Charon’s humanity and unflappable charisma. Lance leaves behind an indelible legacy and hugely impressive body of work, but we will remember him as our lovely, joyful friend and Concierge. We’re stunned and heartbroken, and our deepest condolences go to his beloved family and his fans all around the world.,” the company said in a statement.

Law enforcement officials told TMZ that Reddick was found in his home in Studio City around 9:30 a.m.

In his final Instagram post on Thursday, Reddick had just shared a sweet tribute to his dogs, writing, “On screen and off, it’s no surprise I love spoiling my dogs.”

Before achieving fame for his portrayal of hotel manager Charon in the “John Wick” franchise, the actor previously played the role of Cedrick Daniels, a fictional police officer in Baltimore, for five seasons of the critically acclaimed TV series “The Wire.” Reddick, who was born in Baltimore on June 7, 1962, obtained a bachelor’s degree in music from the University of Rochester and later earned a master’s degree in fine arts from Yale after relocating to Boston.

Following his success on screen, Reddick released his album “Contemplations and Remembrances” in 2007, regularly sharing his musical talents on social media. His big break on television was his role as undercover detective Johnny Basil in the HBO drama “Oz” in 2000, which spanned 12 episodes.

Playing the role of police lieutenant Cedric Daniels in the HBO series “The Wire” for five seasons was Reddick’s initial major breakthrough in his career. He holds a special attachment to this project as it was his debut television pilot.

“It wasn’t like I had all these other experiences in television and then, suddenly, this incredible experience. My career at that point had largely been the theater, some guest stuff, and movies,” he told CBR last year regarding his fortunate career turn.

“The grueling and nightmarish stories I heard later about working in television, I just didn’t know. Walking into what arguably became the greatest dramatic series in the history of American television, knowing how good it was from having just read the pilot, I thought, ‘Cool, I’m doing the s–t I want to do. I’m lucky because I’ve been able to do really great work, and I’m getting to do more of it!’ I didn’t know I was spoiled until I left, until it was over.”

Reddick has continued to secure roles in law enforcement on-screen, including his performance as special agent Phillip Broyles in “Fringe” in 2008, and as a police chief in Amazon Prime’s “Bosch.”

He has also made recent appearances in popular shows such as Netflix’s “Resident Evil” and Amazon’s “The Legend of Vox Machina.” His upcoming film, “John Wick: Chapter 4,” is set to release next week.

“The character was just the kind of character that I never got to play,” he told IMDb about his “John Wick” character in 2019. “Ever since ‘The Wire,’ I’ve played a lot of intimidating authority figures that talk a lot, so to play this kind of quintessential servant whose very taciturn I found fascinating.”

Reddick had several upcoming projects lined up for this year, including a reboot of “White Men Can’t Jump” and a Netflix film titled “Shirley,” in addition to reprising his role as Charon in the spin-off “Ballerina” alongside Ana de Armas. After the news of Reddick’s passing, his colleagues and fans expressed their condolences on social media.

His former co-star on “The Wire,” Wendell Pierce, described him as a “man of great strength and grace” and the embodiment of class.

“A consummate professional, a devoted collaborator, a lovely soul and a friend,” said “The Wire” creator David Simon in a statement to The Hollywood Reporter. “This is just gutting and way, way, way too soon for any of us who knew and loved him to contemplate.”

“Suicide Squad” and “Guardians of the Galaxy” director James Gunn also paid tribute, saying Reddick was “an incredibly talented actor.”

In light of Reddick’s passing, his representatives have requested that the family’s privacy be respected, and instead suggested making donations in his memory to momcares.org.

He leaves behind his wife, Stephanie Reddick, and their children, Yvonne Nicole Reddick and Christopher Reddick.